Table 1.

Arginine methylation sites identified from IAP-LC-MS/MS experiments in CRC tissues

Source	Methylation type	Peptides	New substrates / total proteins	New sites / total sites	Common proteins	Common sites
CRC tissues from patients	MMAa	759	462/272	122/455	68	57
	ADMA	522	29/155	94/314

^aIndicates total number of peptides, proteins, and sites pulled down by MMA-specific and ADMA-specific antibodies (See text). Newly identified arginine methylation sites and substrates for PRMTs in CRC tissues were searched using PhosphoSitePlus® database [24]