%BIAS (Top), %SD (Middle), and %RMSE (Bottom) for the activity concentration calculated across the 35 simulated lesions vs iteration (iteration 1 to 5 and every 5th iterations afterwards up to 100 iterations), for the three reconstruction methods investigated in this work and the post-reconstruction deconvolution approaches. Left: Spherical VOIs centered at the simulated lesion coordinates. Right: Spherical VOIs centered on the coordinate for which the corresponding lesion mean activity concentration is maximal. noRM, invRM, and varRM are reconstructions without, with spatially-invariant, and with spatially-variant resolution modeling, respectively. varLW and varRL are respectively Landweber and Richardson-Lucy post-reconstruction deconvolution approaches using the same spatially-variant kernels as the varRM reconstruction.