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. 2020 May 19;15:60. doi: 10.1186/s13000-020-00949-5

Table 2.

Univariate and multivariate analyses of prognostic variables for overall survival in GA patients using Cox proportional hazards regression

Characteristic Univariate analyses Multivariate analyses
HR 95% CI P HR 95% CI P
Age (years) 0.202 0.494
 < 65 1.00 1.00
 ≥ 65 1.326 0.859–2.044 1.178 0.737–1.882
Tumor size (cm) 0.007* 0.888
 < 4.5 1.00 1.00
 ≥ 4.5 1.918 1.190–3.091 1.042 0.591–1.835
pT stage < 0.001* < 0.001*
 1 1.00 1.00
 2 4.944 1.440–16.974 1.639 1.154–22.990
 3 12.358 3.875–39.412 2.352 2.472–44.689
 4 20.989 4.690–93.938 3.854 7.152–311.452
Lymph node metastasis < 0.001* < 0.001*
 Negative 1.00 1.00
 Positive 5.610 3.446–9.133 3.272 1.908–5.613
Distant metastasis < 0.001* 0.002*
 Negative 1.00 1.00
 Positive 5.050 2.952–8.640 2.528 1.416–4.513
Gli1 < 0.001* 0.002*
 Negative 1.00 1.00
 Positive 5.245 2.401–11.458 3.572 1.573–8.112

*Statistically significant findings