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. 2020 May 19;17(5):e1003104. doi: 10.1371/journal.pmed.1003104

Table 2. Risk of SMM or maternal mortality arising between 23 weeks’ gestation up to 42 days postpartum (main model, upper), as well as between the index birth up to 42 days postpartum (Additional analysis 1, lower), each in association with a 0.5% increase in preconception A1c.

RRs were adjusted for maternal age and world region of origin—each at the time of the A1c test—as well as drug or tobacco dependence <1 year before conception and multifetal pregnancy. This analysis comprises 31,225 pregnancies in the preconception sub-cohort.

Timing of assessment of SMM or death Number (overall %) with SMM or death Unadjusted RR (95% CI) p-Value aRR (95% CI) p-Value
From 23 weeks’ gestation up to 42 days postpartum 682 (2.2) 1.16 (1.14–1.19) <0.001 1.16 (1.13–1.18) <0.001
From the index birth up to 42 days postpartum 400 (1.3) 1.12 (1.08–1.16) <0.001 1.11 (1.07–1.16) <0.001

Abbreviations: aRR, adjusted relative risk; RR, relative risk; SMM, severe maternal morbidity