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. 2020 May 19;15(5):e0233310. doi: 10.1371/journal.pone.0233310

Table 3. Hazard ratios of left ventricular mass and its several indexations for adverse clinical outcomes.

Univariate Multivariate
HR (95% CI) P HR (95% CI) P
Composite outcome
LVM (g) 1.007 (1.005–1.008) <0.001 1.004 (1.002–1.005) <0.001
LVMI-BSA (g/m2) 1.019 (1.015–1.022)* <0.001 1.011 (1.006–1.016)* <0.001
LVMI-H2.7 (g/m2.7) 1.042 (1.033–1.051)* <0.001 1.023 (1.012–1.035)* <0.001
Renal outcome
LVM (g) 1.009 (1.007–1.011)* <0.001 1.006 (1.003–1.009)* <0.001
LVMI-BSA (g/m2) 1.022 (1.017–1.026)* <0.001 1.015 (1.009–1.020)* <0.001
LVMI-H2.7 (g/m2.7) 1.049 (1.039–1.059)* <0.001 1.032 (1.019–1.045)* <0.001
CV outcome
LVM (g) 1.006 (1.003–1.008) <0.001 1.005 (1.000–1.009) 0.037
LVMI-BSA (g/m2) 1.014 (1.009–1.019) <0.001 1.010 (1.002–1.017) 0.012
LVMI-H2.7 (g/m2.7) 1.031 (1.020–1.043) <0.001 1.023 (1.006–1.040) 0.007
All-cause mortality
LVM (g) 1.006 (1.002–1.009) 0.001 1.001 (0.995–1.006) 0.765
LVMI-BSA (g/m2) 1.014 (1.007–1.021) <0.001 0.999 (0.990–1.009) 0.905
LVMI-H2.7 (g/m2.7) 1.026 (1.010–1.042) 0.001 0.996 (0.975–1.018) 0.710

LVM, left ventricular mass; LVMI, left ventricular mass index; BSA, body surface area; H, height; W, weight; CV, cardiovascular. HR and its CI were calculated using Cox proportional hazard regression analysis. In multivariate analysis, covariates were age, sex, current smoking, causes of chronic kidney disease, systolic blood pressure ≥ 127 mmHg, diastolic blood pressure ≥ 77 mmHg, blood urea nitrogen≥ 8.6 mmol/l, estimated glomerular filtration rate ≥ 46.3 ml/min/1.73m2, bilirubin ≥ 10.3 μmol/l, albumin ≥ 42 g/l, cholesterol ≥ 4.4 mmol/l, hemoglobin ≥ 12.8 g/dl, body mass index, fasting glucose, urine protein creatinine ratio, and high sensitive C-reactive protein.

* meant results using time-dependent Cox hazard regression analysis.