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. 2020 May 19;15(5):e0233227. doi: 10.1371/journal.pone.0233227

Table 1. Characteristics of participants in early life and young adulthood.

Variables Males Females
N N
Measurements in young adulthood
Average IMT (mm)1 120 0.57 (0.06) 145 0.55 (0.05)
Age at IMT measurement (yrs) 120 23.3 (5.7) 145 23.9 (5.1)
Waist circumference (cm) 120 83.6 (8.3) 145 75.3 (8.3)
BMI at IMT measurement (kg/m2) 104 24.2 (3.3) 142 23 (4.2)
Systolic blood pressure (mm Hg) 103 121.3 (10.7) 140 110.5 (9.8)
Diastolic blood pressure (mm Hg) 103 75.9 (9.4) 140 72.8 (8.1)
Participation in sport (yes/no) 2 91 88 (96.7%) 123 118 (96.0%)
Energy expenditure (kcal) 3 55 641 (263) 68 363 (260)
Early life factors
Maternal age at child birth (yrs) 120 30.6 (4.2) 142 30.3 (4.2)
Paternal age at child birth (yrs) 119 33.3 (5.1) 137 33.2 (5.0)
Pregnancy duration (wks) 120 40 (40, 41) 145 40 (39, 41)
Gestational weight gain (kg) 117 12.9 (4.0) 141 12.9 (3.6)
High gestational weight gain n (%)4 117 20 (17.1%) 141 20 (14.2%)
Birthweight (g) 120 3583 (443) 145 3411 (437)
    Birth weight < 3000 (g) 5 (4.2%) 28 (19.3%)
    Birth weight ≥ 3000 to ≤ 4000 (g) 93 (77.5%) 104 (71.7%)
    Birth weight > 4000 (g) 22 (18.3%) 13 (9%)
Birth weight by gestation age5 120 145
    SGA 12 (10%) 16 (11.0%)
    AGA 92 (76.7%) 111 (76.6%)
    LGA 16 (13.3%) 18 (12.4%)
Full breastfeeding 104 130
    Never (0–2 weeks) 29 (27.8%) 37 (28.4%)
    Short duration (3–17 weeks) 40 (38.5%) 49 (37.7%)
    Long duration (˃17 weeks) 35 (33.7%) 44 (33.9%)
Additional potential confounders
Birth year 120 1989 (1985, 1992) 145 1988 (1985, 1991)
Firstborn status (yes/no) 104 58 (55.8%) 129 74 (57.4%)
Maternal overweight (yes/no)6 116 38 (32.8%) 141 41 (29.1%)
High paternal educational status (yes/no)7 119 70 (58.8%) 136 73 (53.7%)
Smokers in the household (yes/no) 106 37 (34.9%) 134 55 (41.0%)

Values are presented as means (SD) medians (IQR) or frequencies (percentage).

AGA: appropriate for gestational age, LGA: large for gestational age, SGA: small for gestational age.

AGA, LGA and SGA defined according to German sex-specific birth weight and length-for-gestational-age curves.

1Average IMT: mean of intima media thickness (IMT).

2Participation in organized or unorganized sport: (yes/no).

3Estimated energy expenditure during participation in organized or unorganized sport.

4High gestational weight gain: yes (>16kg), no (≤16kg).

5 Birth weight by gestation age

6Maternal overweight: yes (≥ 25kg), no (<25kg).

7High educational status: yes (≥12yrs of school attendance), no (<12yrs of school attendance).