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. 2020 May 19;15(5):e0233345. doi: 10.1371/journal.pone.0233345

Table 3. Univariate difference-in-difference analysis of the communication training on the antibiotic prescribing behavior.

Prescribing rate (in %)
Intervention Group Control Group Difference-in-Difference
unmatched matched unmatched matched
Before 55.43 47.27 52.86
(2014–2015) (n = 2284) (n = 235355) (∑wi≈2282)
After 44.27 42.61 47.80
(2016) (n = 698) (n = 75167) (∑wi≈736)
Difference -11.16** -4.65** -5.07* -6.51** -6.10*
p-value <0.001 <0.001 0.017 0.003 0.043

313,504 observations (234,723 patients from 1,477 general practitioners). Significance levels: * 5%, ** 1%. Matching is based on Entropy balancing using the variables listed in Table 2 and wi denotes the Entropy balancing weights.