Table 1. Within-host and population diversity.

Period	N	Polyclonal N [%; CI95%]	MOI Mean (SD)	MOI Median (Max)	MLOCI Median (Max)	HE Mean (SD)	Rs Mean (SD)
P. vivax
2004–2006	119	80 [67; 59–76]	1.9 (0.7)	2 (4)	3 (7)	0.864 (0.06)	14.6 (6.2)
2006–2009	143	81 [57; 49–65]	1.8 (0.8)	2 (4)	3 (7)	0.858 (0.06)	15.6 (6.5)
2009–2012	114	44 [38; 29–47]	1.4 (0.6)	1 (4)	2 (7)	0.852 (0.07)	16.2 (7.2)
2012–2015	146	58 [40; 32–48]	1.4 (0.6)	1 (4)	2 (7)	0.854 (0.06)	15.8 (6.1)
2015–2017	93	33 [35; 26–45]	1.4 (0.7)	1 (5)	1 (5)	0.860 (0.07)	17.0 (8.3)
P. falciparum
2004–2006	135	38 [28; 21–36]	1.3 (0.5)	1 (3)	1 (5)	0.594 (0.2)	7.3 (2.5)
2006–2009	128	38 [29; 21–37]	1.3 (0.5)	1 (3)	2 (5)	0.628 (0.3)	7.5 (2.5)
2009–2012	102	28 [27; 19–36]	1.3 (0.4)	1 (2)	1 (4)	0.623 (0.3)	6.4 (2.2)
2012–2015	176	35 [20; 14–26]	1.2 (0.4)	1 (2)	1 (5)	0.545 (0.3)	5.2 (2.1)
2015–2017	125	22 [18; 11–24]	1.2 (0.4)	1 (3)	1 (5)	0.602 (0.2)	7.0 (2.3)

MOI: Multiplicity of Infection; MLOCI: Number of multiallelic loci; CI95%: 95% Confidence interval of the proportion of polyclonal infections Rs: Allelic richness; H_E: Expected heterozygosity