Table 1.
Polyglutamine-Length-Dependent Effects of Htt on Circadian Rhythmicity
Period | P-S | N | R% | |
---|---|---|---|---|
Pdf-Gal4/U-HttQ0#10-2 | 24.5 ± 0.1 | 97 ± 10 | 16 | 94% |
Pdf-Gal4/U-HttQ128#35 | – | 0 ± 0*** | 14 | 0% |
Pdf-Gal4/+;U-HttQ25-eGFP/+ | 24.2 ± 0.1 | 93 ± 10 | 14 | 100% |
Pdf-Gal4/+;U-HttQ46-eGFP/+ | 24.2 ± 0.1 | 99 ± 12 | 17 | 94% |
Pdf-Gal4/+;U-HttQ72-eGFP/+ | 24.8 ± 0.1 | 84 ± 13 | 15 | 96% |
Pdf-Gal4;U-HttQ103-eGFP/+ | 24.0 ± 0.1 | 42 ± 9*** | 16 | 75% |
p < 0.05,
p < 0.01,
p < 0.005 compared to non-pathogenic Htt control lines, respectively.