Table 1.
The CMAP Analysis of the Different Gene Expression Triggered by UA
Rank | CMAP Inhibitor | Description | Score |
---|---|---|---|
1 | HU-211 | NFkB pathway inhibitor | 99.66 |
2 | BRD-K98824517 | Tyrosine phosphatase inhibitor | 99.51 |
3 | Angiogenesis-inhibitor | Angiogenesis inhibitor | 99.07 |
4 | Flubendazole | Tubulin inhibitor | 98.82 |
5 | AG-957 | Abl kinase inhibitor | 98.75 |
6 | GDC-0879 | RAF inhibitor | 98.66 |
7 | Withaferin-a | IKK inhibitor, NFkB pathway inhibitor, PKC inhibitor | 98.51 |
8 | Cladribine | Adenosine deaminase inhibitor, DNA synthesis inhibitor | 98.37 |
9 | ON-01910 | PLK inhibitor | 97.83 |
10 | Cyclopiazonic acid | ATPase inhibitor | 97.75 |
Abbreviations: CMAP, connectively map; UA, ursolic acid; NF-κB, nuclear factor kappa-B; RAF, RAF, serine/threonine kinase protein; IKK, inhibitor of nuclear factor kappa-B kinase; PLK, polo-like kinase; PKC, protein kinase C; ATPase, adenosine triphosphate synthase.