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. 2019 Nov 27;17(4):441–450. doi: 10.1080/15476286.2019.1694733

Figure 3.

Figure 3.

TRMT2B inactivation leads to statistically significant reduction of the respiratory chain complexes I, III and IV activity. Shown are oxygen consumption rates of the permeabilized wild type (open bars) and Trmt2B knockout (grey bars) cells. Substrates and inhibitors of the complexes I-IV were added sequentially, see materials and methods.