Table 1.
m5U methylation of mito-tRNA T-loop by TRMT2B protein.
| tRNA amino acid | Т-loop | m5U methylation by TRMT2B | |
|---|---|---|---|
| T-loop starts with UUC | Ile | UUCAAGC | + |
| Gln | UUCAAUU | + | |
| Leu(tm5UAA) | UUCAAAU | + | |
| Ser(UGA) | UUCGAUU | partial | |
| Т-loop starts with UU, but the third nucleotide is not С | Tyr | UUUAAAU | + |
| Asn | UUUAAUU | + | |
| Met | UUUAAAU | + | |
| Ser(GCU) | UUUAAAAA | - | |
| Glu | UUGAAUG | not analysed | |
| Т-loop starts with U, but the second nucleotide is not U | Thr | UCUUC | - |
| Asp | UCAAUAA | - | |
| Arg | UGAUGU | not analysed | |
| Leu(UAG) | UGCAAAU | ||
| Т-loop doesn’t start with U | Gly | AUAAAC | - |
| Ala, Cys, His, Lys, Phe, Pro, Trp, Val | not analysed |