Table 1.
List of 58 human RNMT proteins and their methylated RNA type and position.
| RNMT | Gene Location | Full Name | RNA Type | Methylation Position | PubMed ID |
|---|---|---|---|---|---|
| ALKBH8 | 11q22.3 | ALKB Homolog 8 | rRNA/tRNA | mcm5U | 20,123,966 |
| BCDIN3D | 12q13.12 | BCDIN3 Domain Containing RNA Methyltransferase | tRNA/small RNAs (pre-miRNA) | 23,063,121 | |
| BUD23 | 7q11.23 | BUD23 rRNA Methyltransferase and Ribosome Maturation Factor | rRNA | m7G | 18,332,120 |
| CDK5RAP1 | 20q11.21 | CDK5 Regulatory Subunit Associated Protein | tRNA | ms2 | 22,422,838 |
| CDKAL1 | 6p22.3 | CDK5 Regulatory Subunity Associated Protein 1 like 1 | tRNA | ms2 | 21,841,312 |
| CMTR1 | 6p21.2 | Cap Methyltransferase 1 | mRNA | 2ʹOm | 20,713,356 |
| CMTR2 | 16q22.2 | Cap Methyltransferase 2 | mRNA | 2ʹOm | 21,310,715 |
| DIMT1 | 5q12.1 | DIMT1 rRNA Methyltransferase and Ribosome Maturation Factor | rRNA | m6A | 25,851,604 |
| ELP3 | 8p21.1 | Elongator Acetyltransferase Complex Subunit 3 | tRNA | m5C | 15,769,872 |
| EMG1 | 12p13.31 | EMG1 N1-Specific Pseudouridine Methyltransferase | rRNA | m1 | 20,047,967 |
| FBL | 19q13.2 | Fibrillarin | rRNA | 2ʹOm | 8,431,947 |
| FBLL1 | 5q34 | Fibrillarin like 1 | rRNA | 2ʹOm | 26,566,070 |
| FTSJ1 | Xp11.23 | FtsJ RNA 2ʹ-O-Methyltransferase 1 | tRNA | 2ʹOm | 11,927,565 |
| FTSJ3 | 17q23.3 | FtsJ RNA 2ʹ-O-Methyltransferase 3 | rRNA/mRNA | 2ʹOm | 30,626,973 |
| HENMT1 | 1p13.3 | HEN Methyltransferase Homolog 1 | small RNAs (piRNA) | 2ʹOm | 18,029,764 |
| MEPCE | 7q22.1 | Methlphosphate Capping Enzyme | small RNAs (snRNA) | 29,425,494 | |
| METTL1 | 12q14.1 | Methyltransferase like 1 | tRNA/mRNA | m7G | 31,031,084 |
| METTL14 | 4q26 | Methyltransferase like 14 | mRNA | m6A | 24,316,715 |
| METTL3 | 14q11.2 | Methyltransferase like 3 | mRNA | m6A | 24,316,715 |
| METTL4 | 18p11.32 | Methyltransferase like 4 | 26,566,070 | ||
| MRM1 | 17q12 | Mitochndrial rRNA Methyltransferase 1 | rRNA | 2ʹOm | 25,074,936 |
| MRM2 | 7p22.3 | Mitochndrial rRNA Methyltransferase 2 | rRNA | 2ʹOm | 25,074,936 |
| MRM3 | 17p13.3 | Mitochondrial rRNA Methyltransferase 3 | rRNA | 2ʹOm | 25,074,936 |
| NOP2 | 12p13.31 | NOP2 Nucleolar Protein | rRNA | m5C | 23,913,415 |
| NSUN2 | 5p15.31 | NOP2/Sun RNA Methyltransferase 2 | tRNA | m5C | 17,071,714 |
| NSUN3 | 3q11.2 | NOP2/Sun RNA Methyltransferase 3 | tRNA | m5C | 27,497,299 |
| NSUN4 | 1p33 | NOP2/Sun RNA Methyltransferase 4 | rRNA | m5C | 24,516,400 |
| NSUN5 | 7q11.23 | NOP2/Sun RNA Methyltransferase 5 | rRNA | m5C | 23,913,415 |
| NSUN5P1 | 7q11.23 | NSUN5 Pseudogene 1 | rRNA | 26,566,070 | |
| NSUN5P2 | 7q11.23 | NSUN5 Pseudogene 2 | rRNA | 26,566,070 | |
| NSUN6 | 10p12.31 | NOP2/Sun RNA Methyltransferase 6 | tRNA | 26,566,070 | |
| NSUN7 | 4p14 | NOP2/Sun RNA Methyltransferase Family Member 7 | 26,774,474 | ||
| RNMT | 18p11.21 | RNA Guanine-7 Methyltransferase | mRNA | m7G | 27422871 |
| RSAD1 | 17q21.33 | Radical S-adenosyl Methionine Domain Containing 1 | 26566070 | ||
| SPOUT1 | 9q34.11 | SPOUT Domain Containing Methyltransferase 1 | |||
| TARBP1 | 1q42.2 | TAR (HIV-1) RNA Binding Protein1 | tRNA | 2ʹOm | 31019095 |
| TFB1M | 6q25.3 | Transcription Facotr B1, Mitochondrial | rRNA | m6A | 17031457 |
| TFB2M | 1q44 | Transcription Facotr B2, Mitochondrial | rRNA | m6A | 17031457 |
| TGS1 | 8q12.1 | Trimethylguaosine Synthase 1 | small RNAs (snoRNA/snRNA) | m7G | 11983179 |
| THUMPD2 | 2p22.1 | THUMP Domain Containing 2 | tRNA | 26566070 | |
| THUMPD3 | 3p25.3 | THUMP Domain Containing 3 | tRNA | 26566070 | |
| TRDMT1 | 10p13 | tRNA Aspartic Acid Mthyltransferase 1 | tRNA | m5C | 16424344 |
| TRMT1 | 19p13.13 | tRNA Methyltransferase 1 | tRNA | mmG | 28784718 |
| TRMT10A | 4q23 | tRNA Methyltransferase 10A | tRNA | m1A | 31292261 |
| TRMT10B | 9p13.2 | tRNA Methyltransferase 10B | tRNA | m1A | 31292261 |
| TRMT10C | 3q12.3 | tRNA Methyltransferase 10C | tRNA | m1A | 29880640 |
| TRMT11 | 6q22.32 | tRNA Methyltransferase 11 Homolog | tRNA | 2ʹOm | 15899842 |
| TRMT112 | 11q13.1 | tRNA Methyltransferase Subunit 11-2 | rRNA | m7G | 22493060 |
| TRMT12 | 8q24.13 | tRNA Methyltransferase 11 Homolog | tRNA | 26566070 | |
| TRMT1L | 1q25.3 | tRNA Methyltransferase like 1 | tRNA | 26566070 | |
| TRMT2A | 22q11.21 | tRNA Methyltransferase 2 Homolog A | tRNA | m5U | 31361898 |
| TRMT2B | Xq22.1 | tRNA Methyltransferase 2 Homolog B | tRNA | m5C | 31361898 |
| TRMT44 | 4p16.1 | tRNA Methyltransferase 44 Homolog | tRNA | 2ʹOm | 26566070 |
| TRMT5 | 14q23.1 | tRNA Methyltransferase 5 | tRNA | m1A | 26189817 |
| TRMT61A | 14q32 | tRNA Methyltransferase 61A | tRNA | m1A | 30131402 |
| TRMT61B | 2p23.2 | tRNA Methyltransferase 61B | tRNA | m1A | 29107537 |
| TRMT9B | 8p22 | tRNA Methyltransferase 9B | tRNA | 23381944 | |
| TYW3 | 1p31.1 | tRNA-yW Synthesizing Protein 3 | tRNA | 27932585 |