Fig. 3.
The machine learning approach in predictive signature discovery. (a, b) ROC curve for type 2 diabetes (T2DM) cases (a) and control participants (b) in the filtered classifier algorithm. The mean AUC was 0.92 for both case (a) and control (b) within the 95% CI. (c) The decision tree generated from the filtered classifier algorithm. (d) The selection of cross-validation through the ‘one standard error’ rule where K=45 was selected. (e) Comparison table for the top biomarkers found using the different approaches