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. 2020 May 20;13(6):803–807. doi: 10.1016/j.molp.2020.05.014

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© 2020 The Author

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Two Examples of Plant-Derived Medicines Currently under Investigation for COVID-19 Treatment.

(A) Quinine was discovered as the principal bioactive compound from Cinchona officinalis, a South American antimalarial medicinal plant. Chloroquine and hydroxychloroquine are synthetic analogs of quinine and have been approved for treating malaria, HIV, systemic lupus erythematosus, and rheumatoid arthritis.

(B) The lung cleansing and detoxifying decoction (LCDD) widely used in treating COVID-19 patients in China was developed based on four formulae described in the classic TCM text Treatise on Cold Pathogenic and Miscellaneous Diseases by Zhang Zhongjing (AD 150–219).