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. 2020 May 19;10:8286. doi: 10.1038/s41598-020-64623-y

Table 1.

MACROD1, MACROD2 and TARG1 nomenclature and predicted/reported localisation.

Protein name Gene name Localisation UNIPROT Localisation Human Protein Atlas Localisation observed
MACROD1;LRP16 MACROD1 Nucleus Nucleoplasm45 Nucleus; cytoplasm (GFP-MACROD1)30 Mitochondria (MACROD1-GFP)32,33 Mitochondria; nucleus (flag-MACROD1)31
MACROD2; C20orf133 MACROD2 Nucleus Nucleoplasm; nucleoli45 Nucleus; cytoplasm (GFP-MACROD2)32,38
TARG1;C6orf130 OARD1 Nucleus Nucleoplasm; nucleoli45 Nucleoplasm; nucleoli (GFP-TARG1)26,39

Table 1 summarises the commonly used protein and gene names of the three hydrolases, as well as their predicted and thus far observed intracellular localisations.