Table 1.
Univariate and multivariate analyses of IGF signaling factors on recurrence-free survival in bladder cancer patients from TCGA_BLCA cohort.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |||
| IGF1 | < | Mean | 1 | 0.1807 | 1 | 0.1715 |
| ≥ | Mean | 1.390 (0.858–2.250) | 1.417 (0.860–2.336) | |||
| IGF2 | < | Mean | 1 | 0.7112 | 1 | 0.4848 |
| ≥ | Mean | 0.911 (0.557–1.490) | 0.832 (0.497–1.393) | |||
| IGF1R | < | Mean | 1 | 0.0066** | 1 | 0.0062** |
| ≥ | Mean | 2.093 (1.228–3.568) | 2.136 (1.241–3.677) | |||
| IGFBP1 | < | Mean | 1 | 0.5761 | 1 | 0.5313 |
| ≥ | Mean | 1.151 (0.702–1.888) | 1.188 (0.693–2.037) | |||
| IGFBP3 | < | Mean | 1 | 0.6081 | 1 | 0.7504 |
| ≥ | Mean | 0.881 (0.543–1.430) | 0.915 (0.531–1.578) | |||
| IGF2BP3 | < | Mean | 1 | 0.8349 | 1 | 0.5824 |
| ≥ | Mean | 1.053 (0.650–1.705) | 0.867 (0.522–1.441) | |||