Table 2.
Correlation of DAS28-MCP-1 scores with DAS28-ESR and DAS28-CRP scores with different ESR/CRP cut-off points.
| DAS28-MCP-1 | Time points | DAS28-ESR | DAS28-ESR (ESR ≧28 mm/hr) |
DAS28-ESR (ESR <28 mm/hr) |
DAS28-CRP | DAS28-CRP (CRP ≧10 mg/L) |
DAS28-CRP (CRP <10 mg/L) |
|---|---|---|---|---|---|---|---|
| All 835 visits | 0.830a (0.808–0.850) |
0.949b (0.934–0.961) |
0.865b (0.843–0.884) |
0.899a (0.885–0.911) |
0.964c (0.951–0.975) |
0.920c (0.907–0.931) |
|
| correlates with | Baseline | 0.850 | 0.940 | 0.874 | 0.901 | 0.945 | 0.926 |
| other scores at | Month 3 | 0.840 | 0.962 | 0.856 | 0.901 | 0.949 | 0.922 |
| different months | Month 6 | 0.862 | 0.964 | 0.876 | 0.910 | 0.962 | 0.933 |
| Month 9 | 0.818 | 0.897 | 0.841 | 0.893 | 0.969 | 0.898 | |
| Month12 | 0.822 | 0.939 | 0.849 | 0.887 | 0.976 | 0.902 | |
| Biologicsd | All 232 visits |
0.779d (0.723–0.825) |
0.947e (0.920–0.965) |
0.806e (0.740–0.857) |
0.892d (0.875–0.923) |
0.919f (0.875–0.935) |
0.860f (0.837–0.880) |
All values are Pearson correlation coefficients, except where indicated. aSpearman’s correlation coefficients; the 95% confidence interval (CI) in parentheses: P < 0.001 (and all below were done as in ref. 20,21). bThe 95% CI: P < 0.001. cThe 95% CI: P < 0.001. dVisits receiving biologics; the 95% CI: P < 0.001. eThe 95% CI: P < 0.001. fThe 95% CI: P = 0.042.