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. 2020 May 19;10:8231. doi: 10.1038/s41598-020-65069-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Functional assessment of the transplanted fetal liver tissue in UPAL coating group. (a) Histological analysis of the fetal liver tissue that was engrafted on the surface of the middle lobe of the liver and covered by UPAL. DPPIV-stained living tissue is shown in red. Scar bar: 5 mm. (b) Measurement of the survival rate of transplanted fetal liver tissue in UPAL group. The survival rate in the transplanted group without UPAL serves as the control. Data are shown as mean ± SEM. *P < 0.01, log rank test, Sham: n = 24, TP: n = 21. (c) Levels of PLT, PT, hyaluronic acid, AST, ALT, T-BIL, NH₃ and ALB were also comparable between the sham and transplanted groups after UPAL coating. Data are mean ± SE. *P < 0.05, vs. sham Mann-Whitney U test, n = 6–9.