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Chromosomal point mutations associated with the quinolone resistance-determining region (QRDR) and azithromycin resistance for S. Typhi.
| AMR gene | AMR SNP’s | Resistance type | Frequency |
|---|---|---|---|
| gyrA | D87N, S83Y, D87Y, S83F, D87G | fluoroquinolone | 94.74% |
| gyrB | S464F, A574V | fluoroquinolone | 6.77% |
| parC | E84G, E84K, S80I | fluoroquinolone | 21.05% |
| parE | A364V, D420N, L416F | fluoroquinolone | 11.28% |
| acrB | R717Q | azithromycin | 0.75% |
