Table 4.

Genotype-associated sequence types (ST), mutation patterns in the genes encoding DNA gyrase (gyrA and gyrB) or topoisomerase (parC and parE) and known plasmid Inc types in S. Typhi.

Genotypes	No. of isolates (%)	MLST ST	gyrA D87N	gyrA S83Y	gyrA D87Y	gyrA S83F	gyrA D87G	gyrB S464F	parC S80I	parC E84G	parC E84K	parE D420N	parE L416F	Inc Types
2.2	4 (3.01)	2	0	0	0	1	0	0	0	0	0	0	0
2.5	3 (2.26)	2	0	0	0	1	1	0	0	0	0	0	0
3	1 (0.75)	1	0	0	0	1	0	0	0	0	0	0	0
3.3	4 (3.01)	2	0	0	0	1	0	0	0	0	0	0	0	IncFIB(pHCM2)
2.2.2	2 (1.50)	2	0	1	0	0	0	0	0	0	0	0	1
2.2.4	1 (0.75)	2	0	1	0	0	0	0	0	0	0	0	0
3.3.1	6 (4.51)	2	0	1	0	0	0	0	0	0	0	0	1
3.3.2	3 (2.26)	2	0	1	1	0	0	0	0	0	0	0	0
4.3.1	19 (14.29)	1	0	1	0	1	1	1	0	0	0	1	0	IncFIA(HI1); IncHI1A/IncHI1B(R27)
4.3.1.1	18 (13.53)	1	0	1	0	1	1	1	0	0	1	0	0	IncHI1A/IncHI1B(R27); IncFIB(pHCM2); Col(BS512)
4.3.1.2	72 (54.14)	1	1	1	0	1	0	0	1	1	1	0	0	IncFIB(pHCM2); IncN; p0111; IncHI1A/IncHI1B(R27)