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. 2020 May 19;10:8288. doi: 10.1038/s41598-020-65171-1

Table 3.

Analysis of variance of the 7 main effects and 21 interaction effects affecting iron-catechol complexation, significant factors and corresponding p-values are indicated in bold (R2 = 0.76 and R2adj = 0.70).

Factor Sum of Squares Mean Square F Value p-value Contribution (%)
A (type of iron salt) 937383 468691 115 6.68 × 10−40 19
B (pH) 811126 405563 99 1.42 × 10−35 16
C (Temperature) 509469 254735 62 3.11 × 10−24 10
D (Ionic strength) 16304 8152 2 0.14 0
E (Concentration iron) 100814 50407 12 6.27 × 10−6 2
F (Ratio [Fe]:[Cat]) 869 434 0 0.90 0
G (MSG) 59483 29742 7 7.78 × 10−4 1
A × B 780182 195045 48 1.15 × 10−32 16
A × C 90012 22503 6 2.50 × 10−4 2
A × D 73998 18500 5 1.36 × 10−3 1
A × E 442251 110563 27 7.57 × 10−20 9
A × F 2235 559 0 0.97 0
A × G 9240 2310 1 0.69 0
B × C 357090 89272 22 2.66 × 10−16 7
B × D 32866 8216 2 0.09 1
B × E 7930 1982 0 0.75 0
B × F 11954 2989 1 0.57 0
B × G 26167 6542 2 0.17 1
C × D 5424 1356 0 0.86 0
C × E 193111 48278 12 4.41 × 10−9 4
C × F 33035 8259 2 0.09 1
C × G 121354 30338 7 8.83 × 10−6 2
D × E 8845 2211 1 0.70 0
D × F 157640 39410 10 1.86 × 10−7 3
D × G 40674 10169 2 0.04 1
E × F 10606 2651 1 0.63 0
E × G 81992 20498 5 5.86 × 10−4 2
F × G 16030 4008 1 0.42 0