Table 3.
Association of CSF based CDH6 protein levels with AD biomarkers in Amsterdam Dementia Cohort.
| Biomarkers* | Overall | APOE4 stratum | APOE33 stratum | APOE2 stratum | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β | SE | P-value | β | SE | P-value | β | SE | P-value | β | SE | P-value | |
| Aβ-42 | 16.574 | 26.827 | 5.37 × 10−1 | 33.701 | 35.001 | 3.37 × 10−1 | 14.499 | 44.966 | 7.48 × 10−1 | −103.767 | 69.354 | 1.45 × 10−1 |
| p-tau | 23.189 | 3.404 | 3.48 × 10−11 | 26.674 | 5.781 | 8.36 × 10−6 | 21.981 | 5.564 | 1.17 × 10−4 | 25.663 | 7.697 | 2.29 × 10−3 |
| T-tau | 207.396 | 36.437 | 2.40 × 10−8 | 235.009 | 59.158 | 1.10 × 10−4 | 193.859 | 64.068 | 2.90 × 10−3 | 298.437 | 86.637 | 1.66 × 10−3 |
Abbreviations: AD, Alzheimer’s disease; β, regression coefficient; SE, standard error.
*Linear regression analysis adjusting for age and sex.