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. 2020 May 19;7:33. doi: 10.1186/s40658-020-00301-2

Table 3.

Absorbed dosea (Gy) to the nucleus of the central cell in a cluster for different distributions of 177Lu and 161Tb

Cell surface Intracytoplasmic Whole cell Intranuclear
177Lu 7.2 (26%) 8.3 (36%) 11.0 (53%) 15.7 (68%)
161Tb 15.1 (33%) 17.9 (46%) 29.1 (67%) 47.8 (81%)
Enhancement factor 161Tb/177Lu 2.1 2.2 2.6 3.0

aThe target cell is surrounded by a first neighbourhood of 6 cells and a second neighbourhood of 12 cells. The absorbed dose was computed considering a total electron energy release of 1436 MeV from the specific regions of interest from every cell of the cluster. The relative contribution of the self-dose is shown in parentheses