Table 3.
Multivariable logistic regression model for factors independently associated with clinical failure
| Variable | Unadjusted odd ratio (95% CI) |
Adjusted odds ratio (95% CI) |
|---|---|---|
| Source | ||
| Endocarditis | 3.369 (2.127–5.336) | 3.294 (2.115–5.132) |
| Skin and soft tissue | 0.775 (0.499–1.203) | |
| Prosthetic device | 1.746 (0.796–3.829) | |
| Pneumonia | 1.434 (0.884–2.326) | |
| Co-morbidity | ||
| CKD | 1.190 (0.807–1.754) | |
| Prior MRSA in 365 days | 1.566 (0.956–2.563) | 1.545 (0.954–2.500) |
| Prior surgery in 365 days | 0.716 (0.365–1.406) | |
| Other factors | ||
| Admission, home | 0.775 (0.521–1.154) | |
| Age > 60 years | 1.222 (0.844–1.769) | |
| APACHE II score | 1.034 (1.011–1.058) | 1.045 (1.029–1.072) |
| Treatment | ||
| Combination therapy | 0.539 (0.356–0.816) | 0.545 (0.364–0.817) |
Hosmer–Lemeshow goodness of fit test P = 0.983; variance inflation factor = 1.0–1.5 for all variables included at model entry
APACHE II acute physiology and chronic health evaluation II, CKD chronic kidney disease