Table 2.
Multivariate analysis of the relationship between PD-L1 expression and selected factors which have significance via univariate analysis by logistic regression SUVmax as an independent predictor of PD-L1 expression by multivariate analysis
| Factor | Odds ratio | 95% confidence interval | P value | |
|---|---|---|---|---|
| Overall (n= 374) | Sex | 0.38 | 0.07–2.11 | 0.268 |
| Smoking | 3.86 | 0.70–21.18 | 0.121 | |
| Location | 2.55 | 0.757–8.582 | 0.131 | |
| SUVmax | 1.14 | 1.08–1.20 | 0.000* | |
| TLG-P | 0.98 | 0.96–1.01 | 0.109 | |
| TLG-C | 1.02 | 0.99–1.05 | 0.129 | |
| AC (n= 283) | Sex | 0.28 | 0.02–3.33 | 0.313 |
| Smoking | 4.70 | 0.39–55.97 | 0.221 | |
| SUVmax | 1.16 | 1.07–1.24 | 0.000* | |
| TLG-P | 0.97 | 0.93–1.01 | 0.104 | |
| TLG-C | 1.03 | 0.99–1.07 | 0.147 | |
| SCC (n= 91) | Sex | 0.18 | 0.01–7.21 | 0.358 |
| Smoking | 3.40 | 0.30–38.09 | 0.320 | |
| Location | 1.97 | 0.57–6.79 | 0.281 | |
| SUVmax | 1.12 | 1.01–1.24 | 0.032* | |
| TLG-P | 0.99 | 0.95–1.02 | 0.381 | |
| TLG-C | 1.01 | 0.98–1.05 | 0.407 |
AC and SCC represent adenocarcinoma and squamous cell carcinoma and *P < 0.05