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Median (± 90% CI) predicted systemic concentrations (Csys) of midazolam following intravenous infusion at 0.05 mg/h/kg in 19 normothermic neonates (mean body weight 3.91 ± 0.86 kg) for 72 h (total dose 3.6 mg/kg). The solid line and the dashed lines represent the median and 5/95% percentiles. The median concentration at steady state was 0.48 µg/ml.
