Table 4.
Reasons for medication discontinuation as recorded in the chart.
| Medication | Still taking, n (%) | Unknown reason, n (%) | GI symptoms, n (%) | No longer necessary, n (%) | Non-compliance, n (%) | No effect, n (%) |
|---|---|---|---|---|---|---|
| Young adults (19–25 years old) | ||||||
| Metformin | 195 (44.7) | 135 (31.0) | 36 (8.3) | 21 (4.8) | 15 (3.4) | 14 (3.2) |
| Topiramate | 114 (35.6) | 116 (36.3) | 2 (0.6) | 28 (8.8) | 7 (2.2) | 15 (4.7) |
| Bupropion | 94 (30.6) | 141 (45.9) | 0 (0) | 24 (7.8) | 12 (3.9) | 11 (3.58) |
| Phentermine | 40 (34.8) | 33 (28.7) | 2 (1.7) | 14 (12.2) | 3 (2.6) | 4 (3.5) |
| Zonisamide | 8 (33.3) | 11 (45.8) | 0 (0) | 2 (8.3) | 0 (0) | 1 (4.2) |
| Naltrexone | 5 (19.2) | 16 (61.5) | 0 (0) | 4 (15.4) | 0 (0) | 0 (0) |
| Orlistat | 0 (0) | 13 (72.2) | 0 (0) | 2 (11.1) | 0 (0) | 0 (0) |
| Liraglutide | 9 (52.9) | 6 (35.3) | 1 (5.9) | 1 (5.9) | 0 (0) | 0 (0) |
| Overall | 465 (36.8) | 471 (37.3) | 41 (3.3) | 96 (7.6) | 37 (2.9) | 45 (3.6) |
| Adolescents (13–18 years old) | ||||||
| Metformin | 137 (54.2) | 63 (24.9) | 11 (4.4) | 9 (3.6) | 17 (6.7) | 4 (1.6) |
| Topiramate | 57 (41.3) | 47 (34.1) | 1 (0.7) | 7 (5.1) | 6 (4.4) | 5 (3.6) |
| Bupropion | 38 (33.9) | 46 (41.1) | 0 (0) | 10 (8.9) | 2 (1.8) | 2 (1.8) |
| Phentermine | 18 (40) | 16 (35.6) | 1 (2.2) | 0 (0) | 1 (2.2) | 0 (0) |
| Zonisamide | 4 (40) | 5 (50) | 0 (0) | 1 (10) | 0 (0) | 0 (0) |
| Overall | 254 (45.5) | 177 (31.7) | 13 (2.3) | 27 (4.8) | 26 (4.7) | 11 (2.0) |
| Children (5–12 years old) | ||||||
| Metformin | 27 (69.2) | 7 (18.0) | 1 (2.6) | 2 (5.1) | 2 (5.1) | 0 (0) |
| Topiramate | 15 (53.6) | 6 (21.4) | 0 (0) | 3 (10.7) | 0 (0) | 3 (10.7) |
| Bupropion | 6 (40) | 5 (33.3) | 0 (0) | 2 (13.3) | 0 (0) | 0 (0) |
| Overall | 48 (58.6) | 18 (22.0) | 1 (1.2) | 7 (8.5) | 2 (2.4) | 3 (3.7) |