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. 2020 May 13;11:728. doi: 10.3389/fmicb.2020.00728

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Copyright © 2020 Peng, Chen, Wu, Paramita, Yang, Li, Lai and Chang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Therapeutic efficacy of phage TCUEAP1 against mice with sepsis induced by E. anophelis infection. (A) The survival of the mice treated with a single dose of phage TCUEAP1 or normal saline intraperitoneally after E. anophelis infection. The survival of the mice was monitored for 7 days. ***p < 0.001 for normal saline versus phage TCUEAP1. (B) Blood samples of mice treated with normal saline (solid square) versus those of mice treated with phage TCUEAP1 (open triangle) at 6 h after bacterial inoculation. The line indicates mean bacterial load; *p < 0.05 for normal saline versus phage TCUEAP1.