Table 4.

Sex differences for the specific diseases/items in the Comorbidity Index and the Frailty Phenotype over age groups, adjusted for wave and European region, among participants in the Survey of Health, Ageing and Retirement in Europe (SHARE), interviewed from 2004–2005 to 2015

Comorbidity Index	Heart attack	Stroke	Diabetes	Lung disease	Cancer	Ulcer	Arthritis	Hypertension	High Cholesterol	Parkinson
	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)	OR (95% CI)
50–54	0.47 (0.36, 0.62)	0.74 (0.48, 1.13)	0.72 (0.58, 0.89)	0.94 (0.74, 1.20)	2.36 (1.77, 3.14)	0.93 (0.74, 1.16)	1.89 (1.63, 2.19)	0.94 (0.84, 1.07)	0.69 (0.60, 0.80)	0.32 (0.10, 1.03)
55–59	0.46 (0.39, 0.55)	0.74 (0.55, 0.99)	0.64 (0.54, 0.75)	1.04 (0.85, 1.28)	1.67 (1.28, 2.17)	0.89 (0.73, 1.08)	1.89 (1.70, 2.11)	0.93 (0.84, 1.02)	0.86 (0.77, 0.95)	0.56 (0.22, 1.41)
60–64	0.48 (0.42, 0.54)	0.74 (0.59, 0.92)	0.73 (0.65, 0.82)	0.82 (0.70, 0.97)	1.22 (1.03, 1.44)	0.92 (0.76, 1.10)	2.12 (1.94, 2.31)	1.04 (0.96, 1.12)	1.13 (1.04, 1.23)	1.08 (0.63, 1.85)
65–69	0.55 (0.49, 0.61)	0.50 (0.41, 0.62)	0.79 (0.71, 0.88)	0.87 (0.75, 1.01)	1.00 (0.85, 1.19)	0.86 (0.72, 1.03)	2.24 (2.06, 2.43)	1.09 (1.01, 1.17)	1.12 (1.03, 1.21)	0.96 (0.63, 1.47)
70–74	0.62 (0.55, 0.69)	0.77 (0.64, 0.92)	0.90 (0.80, 1.01)	0.81 (0.69, 0.96)	1.00 (0.84, 1.19)	0.80 (0.67, 0.96)	2.37 (2.17, 2.59)	1.20 (1.10, 1.30)	1.28 (1.17, 1.41)	0.99 (0.66, 1.48)
75–79	0.65 (0.58, 0.73)	0.63 (0.52, 0.76)	0.91 (0.80, 1.04)	0.78 (0.66, 0.92)	0.76 (0.63, 0.92)	1.02 (0.83, 1.25)	2.09 (1.89, 2.31)	1.29 (1.18, 1.42)	1.25 (1.13, 1.39)	0.64 (0.46, 0.89)
80–84	0.71 (0.62, 0.82)	0.85 (0.68, 1.07)	1.00 (0.85, 1.17)	0.62 (0.51, 0.75)	0.62 (0.48, 0.80)	0.96 (0.73, 1.28)	2.19 (1.94, 2.47)	1.43 (1.27, 1.61)	1.22 (1.06, 1.41)	0.74 (0.47, 1.17)
85–89	0.83 (0.69, 0.99)	1.05 (0.79, 1.39)	1.15 (0.91, 1.46)	0.67 (0.51, 0.89)	0.52 (0.37, 0.74)	0.87 (0.60, 1.26)	1.78 (1.50, 2.11)	1.46 (1.23, 1.73)	1.47 (1.18, 1.82)	0.70 (0.44, 1.12)
90+	0.93 (0.66, 1.31)	0.80 (0.52, 1.21)	1.27 (0.83, 1.96)	0.60 (0.36, 1.00)	0.94 (0.50, 1.79)	1.02 (0.54, 1.94)	1.64 (1.23, 2.18)	1.24 (0.92, 1.66)	1.36 (0.88, 2.09)	0.55 (0.23, 1.29)
All	0.60 (0.56, 0.63)	0.73 (0.66, 0.80)	0.82 (0.77, 0.88)	0.82 (0.76, 0.87)	1.07 (0.98, 1.16)	0.90 (0.83, 0.98)	2.08 (1.99, 2.18)	1.10 (1.06, 1.15)	1.06 (1.01, 1.11)	0.75 (0.62, 0.92)
Frailty Phenotype	Loss of appetite		Weakness	Fatigue		Slowness	Low physical activity
50–54	1.64 (1.36, 1.98)		1.73 (1.30, 2.31)	1.65 (1.48, 1.83)		1.10 (0.78, 1.55)	1.01 (0.88, 1.16)
55–59	1.78 (1.51, 2.09)		1.49 (1.22, 1.83)	1.68 (1.54, 1.84)		1.43 (1.11, 1.85)	1.03 (0.92, 1.15)
60–64	1.50 (1.30, 1.73)		1.36 (1.18, 1.55)	1.54 (1.43, 1.67)		1.04 (0.84, 1.28)	1.05 (0.95, 1.16)
65–69	1.66 (1.45, 1.90)		1.38 (1.22, 1.56)	1.74 (1.61, 1.88)		1.41 (1.19, 1.66)	1.27 (1.15, 1.40)
70–74	1.62 (1.42, 1.86)		1.25 (1.12, 1.40)	1.77 (1.63, 1.93)		1.54 (1.31, 1.81)	1.35 (1.22, 1.49)
75–79	1.58 (1.38, 1.80)		1.09 (0.98, 1.22)	1.73 (1.57, 1.89)		1.64 (1.42, 1.89)	1.46 (1.32, 1.62)
80–84	1.55 (1.32, 1.82)		1.01 (0.88, 1.15)	1.55 (1.38, 1.74)		1.59 (1.36, 1.86)	1.64 (1.45, 1.86)
85–89	1.36 (1.09, 1.69)		1.07 (0.88, 1.31)	1.34 (1.13, 1.58)		1.97 (1.63, 2.39)	1.79 (1.51, 2.12)
90+	1.48 (1.04, 2.10)		0.69 (0.46, 1.05)	1.27 (0.94, 1.72)		1.68 (1.24, 2.28)	2.09 (1.54, 2.84)
All	1.60 (1.51, 1.70)		1.23 (1.16, 1.30)	1.65 (1.59, 1.71)		1.51 (1.41, 1.63)	1.27 (1.21, 1.32)

OR odds ratio, CI confidence interval