Table 5.

Multivariate Analysis of Risk Factors for Clinical Failure of C/T Therapy Among Patients With Enterobacterales Infection

Variable	OR	95% CI	P Value
Charlson comorbidity index >4	2.3	1.9–3.5	.02
Septic shock	6.2	3.8–7.9	<.001
Empiric therapy displaying in vitro activity	0.12	0.01-0-34	<.001
CRRT	3.1	1.9–5.3	.001
Adequate source control of the infection	0.42	0.14–0.55	<.001

Abbreviations: C/T, ceftolozane/tazobactam; CI, confidence interval; CRRT, continuous renal replacement therapy; OR, odds ratio.