Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A schematic on the role of M-opsin in multiple forms of cone degeneration. Mislocalized M/L-opsins are degraded, which causes proteasome stress and dorsal M cone degeneration. Deletion of M-opsin prevents dorsal M cone degeneration. One strategy to protect M/L cones from degeneration is to promote the folding and targeting of M/L-opsins and to enhance proteasome activity.
