Figure 5.

Nanoparticle‐mediated tumor‐associated cells reprogramming to enhance anti‐tumor functions of T cells. A) M2‐like TAM dual‐targeting nanoparticles (M2NP)‐based delivery of siRNA for CSF‐1R silencing and immune regulation via synergistic dual targeting of M2‐like TAMs in vivo. Reproduced with permission.^[ 111 ^] Copyright 2017, American Chemical Society. B) Polyelectrolyte multilayers assembled entirely from immune signals on gold nanoparticle to activate APCs and to stimulate the formation of antigen‐specific CD8⁺ T cells both in vitro and in vivo. Reproduced with permission.^[ 119 ^] Copyright 2015, American Chemical Society.