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. 2020 Mar 11;7(10):1903233. doi: 10.1002/advs.201903233

Figure 2.

Figure 2

The LOC90024‐encoded SRSP is endogenously, naturally expressed, and SRSP is upregulated in cancers and associated with the prognosis of patients with CRC. A) SRSP immunostaining between SW480 and SW620 cells was determined with an anti‐SRSP antibody. B) SRSP levels were increased in high‐metastatic CRC cells compared with their parental low‐metastatic CRC cells. C) SRSP levels were increased in tumor tissues (T) compared with their matched adjacent nontumoral tissues (NT). D) The unique peptide in the endogenous, natural SRSP in tumor tissues was identified using mass spectrometry. E) Representative IHC images of SRSP expression in CRC T and their matched NT. F) Differences in SRSP scores between T and NT are presented as a box plot. G) Differences in SRSP scores between T and their matched NT are presented as a box plot. H) CRC patients with high SRSP levels had a higher death rate than those with low SRSP levels. I) CRC patients with high SRSP levels had shorter survival times than those with low SRSP levels.