Table 1.
Inoculated Group | Time (dpi) of the First Observation of Fever | Maximum Clinical Score | Time (dpi) of Death | Time (dpi) of the First Detection of Virus in Blood | Time (dpi) of the First Detection of Virus in Oral Swabs | Time (dpi) of the First Detection of Virus in Fecal Swabs | |||
---|---|---|---|---|---|---|---|---|---|
TD/96† | 94.4 | TD/96 | 94.4 | TD/96 | 94.4 | ||||
Group 1: Co-infected_P1 | 4 | 17 | 13 | 2 | 4 | 6 | 8 | 6 | 8 |
(TD/96 106 TCID50 + 94.4 106 TCID50) | 6 | 16 | 13 | 2 | 4 | 6 | 8 | 8 | 10 |
6 | 14 Average 15.67 ± 1.53b* |
13 | 2 | 4 | 6 | 8 | 6 | 8 | |
Group 2: Co-infected_P2 | 2 | 19 | 9 | 2 | 6 | 4 | ND§ | 4 | ND |
(blood of group 1 pig containing TD/96 108.3 TCID50 and 94.4 105.87 TCID50) | 3 | 20 | 12 | 2 | 6 | 4 | 8 | 6 | 8 |
2 | 19 Average 19.33 ± 0.58a |
11 | 2 | 6 | 6 | 8 | 6 | 8 | |
Group 3: Co-infected with Ab | 12 | 5 | 14¶ | 4 | 6 | 6 | 8 | 8 | 8 |
(TD/96 106 TCID50 + 94.4 106 TCID50) | 10 | 5 | 14¶ | 4 | 6 | 6 | 8 | 6 | 8 |
6 | 4 Average 4.67 ± 0.58c |
14¶ | 4 | 6 | 8 | 8 | 8 | 8 |
† TD/96 and 94.4 indicate the TD/96/TWN and 94.4/IL/94/TWN strains, respectively. * Values with different superscript letters, a-c, among the three groups of samples at the same dpi indicate a statistically significant difference (p < 0.05) from each other. The superscript letter “a” indicates the highest viral load and “c” indicates the lowest viral load among the compared groups. ¶ The pig was euthanized at the end of the experiment. § ND: not detected.