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. 2020 Apr 1;12(4):314. doi: 10.3390/pharmaceutics12040314

Figure 1.

Figure 1

The percent viability of C. albicans CAF2-1 (wild type, WT) and KS028 (erg11Δ/Δ) strains after 24 h growth in yeast extract-peptone-dextrose (YPD) in the presence of surfactin (SU) (0–4096 µg/mL). Concentrations of surfactin (SU, µg/mL), leading to either ≥50 or ≥90% growth inhibition towards C. albicans CAF2-1 (WT) and KS028 (erg11Δ/Δ) strains were indicated by dashed lines and were equal to 2048 and 16 (≥50% inhibition) for WT or erg11Δ/Δ, respectively and 4096 and 32 (≥90% inhibition) for WT or erg11Δ/Δ, respectively. Statistical analyses were performed by comparing viability of the erg11Δ/Δ strain to the viability of the WT strain in correspondence with SU concentrations (means ±SD, n = 6) (*, P < 0.05; **, P < 0.01; ***, P < 0.001).