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. 2020 Apr 1;12(4):314. doi: 10.3390/pharmaceutics12040314

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Relative CHS3 (A), CHS4 (B), GSC1 (C), GSL1 (D) or KRE9 (E) gene expression in C. albicans treated with 32 µg/mL SU. The following cell types were treated under the following conditions: C. albicans CAF2-1 strain (WT), C. albicans CAF2-1 strain simultaneously treated with 1 µg/mL fluconazole (WT + FLC) and C. albicans KS028 strain (erg11Δ/Δ mutant). Gene expression levels are reported as means of 2^−∆∆CT values (n = 6) ± SD; normalized to 1 for untreated CAF2-1 strain (WT 0SU). Statistical analyses were performed by comparing expression under each condition to a untreated CAF2-1 strain (WT 0SU) (*, p < 0.05; **, p < 0.01; ***, p < 0.001).