Figure 3.

Therapeutic outcome of PL-cDDP-Ce6 in human S462-TY xenograft tumor-bearing mice. Mice were injected with one dose of PL-cDDP-Ce6 and received two dose of light irradiation (100 J/cm²) at 2 and 12 h post-drug administration, respectively. The dose of cDDP administrated in mice was 3.5 mg/kg and the dose of Ce6 varied under the doses of 1 (A), 1.25 (B) and 1.5 mg/kg (C). Left panel, tumor size; Middle panel, survival rate; Right panel, body weight. The presented data are mean ± S.D. for each group (N = 5).