Table 2.
Percentage of each group ionised at pH 6.85 based on known pKa values of isoniazid.
| Group | pKa | Percentage Ionised |
|---|---|---|
| Hydrazine nitrogen | 1.8 | 0.0009% |
| Pyridine nitrogen | 3.5 | 0.0440% |
| Hydrazide | 10.8 | 0.0110% |
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