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. 2020 Apr 17;12(4):369. doi: 10.3390/pharmaceutics12040369

Table 3.

EC50 (concentration of the drug that elicits half the maximum taste response compared to the reference (water)), 95% confidence interval, and inter-subject and intra-subject variability obtained from the Emax model.

Drug EC50
(mM)
95% Confidence Interval Inter-Subject Variability Intra-Subject Variability
Isoniazid [31] 259 * 80.0–437.9 0.843 95.7
Rifampicin 3.6 * 1.2–6.0 1.36 211
Pyrazinamide 158 * 90.8–225.2 0.336 161
Ethambutol dihydrochloride 27 18.8–35.2 0.335 227

* estimated EC50 value.