Table 3.
EC50 (concentration of the drug that elicits half the maximum taste response compared to the reference (water)), 95% confidence interval, and inter-subject and intra-subject variability obtained from the Emax model.
| Drug | EC50 (mM) |
95% Confidence Interval | Inter-Subject Variability | Intra-Subject Variability |
|---|---|---|---|---|
| Isoniazid [31] | 259 * | 80.0–437.9 | 0.843 | 95.7 |
| Rifampicin | 3.6 * | 1.2–6.0 | 1.36 | 211 |
| Pyrazinamide | 158 * | 90.8–225.2 | 0.336 | 161 |
| Ethambutol dihydrochloride | 27 | 18.8–35.2 | 0.335 | 227 |
* estimated EC50 value.