Table 5.

Comparison of rat IC₅₀ and human EC₅₀ values obtained from fitting of data to the E_max model.

Drug	log(IC50)	log(EC50)	Log Difference
Isoniazid [31]	1.91	2.41	0.50
Rifampicin	0.12	0.56	0.44
Pyrazinamide	-	2.20	-
Ethambutol dihydrochloride	1.13	1.43	0.30
Quinine hydrochloride dihydrate [31]	−1.10	−0.59	−0.51
Caffeine citrate [31]	0.89	0.70	0.19