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. 2020 Mar 27;9(4):247. doi: 10.3390/pathogens9040247

Figure 1.

Figure 1

Levels of dengue virus specific IgM and IgG antibody in cynomolgus macaques, common marmosets, and tamarins: (A) Levels of DENV-specific IgM antibody during primary infection; (B) Levels of DENV-specific IgG antibody during primary infection; (C) Levels of DENV-specific IgM antibody during secondary infection; (D) levels of DENV-specific IgG antibody during secondary infection. Levels of antibody in cynomolgus macaques (○), common marmosets (●), and tamarins (×) were determined from day 0 to 14 after primary and secondary DENV infection. The P/N ratio indicates the positive: negative ratio. The P/N ratio was calculated by using the formula: absorbance of the test sample/absorbance of the negative control. The P/N ratioday0 is defined as the level of DENV-specific IgM or IgG antibody on the day of virus inoculation. DENV, dengue virus; Ig G, immunoglobulin G; Ig M, immunoglobulin M.