Table 2.

Dissolution times of the placebo extrudates at pH 5.5 and pH 6.8, respectively.

Process Condition	pH 6.8	pH 5.5
	Dissolution Time (min)	Dissolution Time (min)
Raw material	7.5	10
120 °C, 1 g/min	20	15
120 °C, 2 g/min	10	15
120 °C, 3 g/min	5	15
140 °C, 1 g/min	incomplete	incomplete
140 °C, 2 g/min	10	20
140 °C, 3 g/min	10	15