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. 2020 Mar 27;12(4):304. doi: 10.3390/pharmaceutics12040304

Figure 7.

Figure 7

Real-time PCR for heme oxigenasse 1 (HMOX-1) (A); NAD(P)H quinone dehydrogenase 1 (NQO1) (B); and Kelch-like ECH-associated protein 1 (KEAP1) (C). The group AuNp 250 µg/kg increased the expression of the HMOX1 or NAD(P)H genes compared to the 5-FU group. The AuNp 250 µg/kg decreased the KEAP1 mRNA expression compared to 5-FU animals. The results are presented as the mean ± standard error of the mean, (n = 5/group). ** p < 0.001; *** p < 0.0001 (analysis of variance with Tukey’s post-test).