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Blood and intragraft B cell IGHV mutation rates. A, Overall percentage of productive rearrangements with SHM for all graft locations and blood for the 4 patients. B, Average percentage of mutated nucleotides among productive mutated rearrangements. Differences between locations were assessed using a two-tailed Mann-Whitney test (***P < .001). IGHV, immunoglobulin heavy chain variable; SHM, somatic hypermutations
