TABLE 1.
Patient characteristics
Patient | Agea (y) | Sex | Original disease | Time to re-Tx (y) | ISHLT CAV scorea | Immunosuppressiona | DSAa | Rejectiona |
---|---|---|---|---|---|---|---|---|
1 | 31 | M | Endocardial cushion defect | 15 | 3 | CsA, MMF, Prednisone | Neg. | ACR |
2 | 57 | M | Nonischemic cardiomyopathy | 15 | 2 | CsA, Aza, Prednisone | Neg. | ACR |
3 | 5 | F | Idiopathic cardiomyopathy | 5 | 2 | FK506, MMF, Rapamycin | Neg. | - |
4 | 28 | F | Restrictive cardiomyopathy | 6 | 1b | CsA, Aza, Prednisone | Neg. | ACR |
ACR, acute cellular rejection; CAV, cardiac allograft vasculopathy; CsA, cyclosporine; DSA, donor-specific antibodies; ISHLT, International Society for Heart and Lung Transplantation; MMF, mycophenolate mofetil; AZA, azathioprine.
At time of retransplantation.
Patient 4 had congestive heart failure due to recurrent restrictive cardiomyopathy.