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. Author manuscript; available in PMC: 2021 Apr 29.
Published in final edited form as: J Am Chem Soc. 2020 Apr 21;142(17):7783–7794. doi: 10.1021/jacs.9b13813

Figure 4.

Figure 4.

Formation and characterization of AcetalDextran-AuNP-Micelles. (a) AcetalDextran-AuNPs and PEG-PCL were dissolved in toluene and then suspended in water to form an emulsion, driving self-assembly of AcetalDextran-AuNP-Micelles. (b) Hydrodynamic diameter of micelles determined via dynamic light scattering. The average peak hydrodynamic diameter was 146 nm. (c) Electron microscopy imaging of micelles in water via Cryo-TEM and standard TEM. (d) Hydrodynamic diameter of micelles in PBS at 4 °C, recorded immediately after suspension and at 1 hour, 1 day, 3 days, 5 days, and 7 days (average of three measurements, ± SEM). At 7 days, the sample was diluted 10-fold in water to reduce salt concentration and then imaged by TEM (inset).