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. Author manuscript; available in PMC: 2021 Apr 29.
Published in final edited form as: J Am Chem Soc. 2020 Apr 21;142(17):7783–7794. doi: 10.1021/jacs.9b13813

Figure 5.

Figure 5.

AcetalDextran-AuNP-Micelles (ADAMs) in cell culture. (a) ADAMs were incubated with HepG2 human liver cells at various concentrations (expressed as μg Au per mL of cell culture solution) for 24 hours, and cytotoxicity was assessed by MTT assay. % Cell viability was calculated in relation to media-only controls; statistical comparison was performed using one-way ANOVA with post-hoc Tukey HSD test; *p < 0.05 relative to media controls. (b,c) ADAMs or control micelles (C12-AuNP-Micelles) were incubated with RAW 264.7 murine macrophages at 10 μg mL−1Au for 24 hours. Cells were fixed and imaged by electron microscopy. Single cell shown for each condition, with expanded images on left.