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. Author manuscript; available in PMC: 2021 Apr 29.
Published in final edited form as: J Am Chem Soc. 2020 Apr 21;142(17):7783–7794. doi: 10.1021/jacs.9b13813

Figure 7.

Figure 7.

Safety profile of AcetalDextran-AuNP-Micelles after injection of 100 mg Au per kg body weight. (a) Percent change in mouse body weight over time, normalized to pre-injection weight. (b-d) Serum measurements of alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase at various times post-injection. Gray shading represents standard clinical range for healthy mice. n = 3 mice per group, ± standard error of the mean. (e) Representative histological images of mouse organ tissues at various timepoints post-injection. Tissues were paraffin-embedded and stained with H&E.