Figure 2.

Renal cell carcinoma cell lines treated with Pazopanib in 2D culture. (a) Cell viability (CellTiter Glo) of 786-O cell line treated for 24 and 48 h with Pazopanib. (b) Cell viability of CAKI-2 cell line treated for 24 and 48 h with Pazopanib. (c) Representative images of 786-O (upper four) and CAKI-2 (lower four) cells, control cells (0 µM Pazopanib) on the left and treated with 40 µM Pazopanib on the right. Scale bar = 200 µm. Two-way ANOVA with Tukey’s post hoc analysis.

Asterisks above open circles indicate significance to control at 24 h of treatment and asterisks below dark circles indicate significance to control cells at 48 h.

*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.